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Whether it is the binding of shattered bones or the creation of herbal remedies, human agency is a central feature of the healing process. Both archaeological and anthropological research has contributed much to our understanding of the performative aspects of medicine. The papers contained in this volume, based on a session conducted at the 2010 Theoretical Archaeology Conference, take a multi-disciplinary approach to the topic, addressing such issues as the cultural conception of disease; the impact of gender roles on healing strategies; the possibilities afforded by syncretism; the relationship between material culture and the body; and the role played by the active agency of the sick.